0990CL - CAS 511514-03-7

0990CL is an effective heterotrimer Gαi subunit specific inhibitor, which can interact with purified Go± in GDP-bound state, and can block α2AR mediated cAMP regulation. In the cell model, low concentration of 0990CL could partially restore cAMP level, and high concentration of 0990CL (10μM) began to have negative effects on cell viability.

CAMP, Others, Adrenergic Receptor

Neuroscience, GPCR/G Protein, Others

511514-03-7

0.9912

C21H21N5

343.42

N(C=1N=C(C2=C(N1)C=CC=C2)C3=CC=CC=C3)C=4NC(C)(C)C=C(C)N4

-20°C

Ice Packs

Small Compound