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1,2,3,4,7,8-Hexachlorodibenzofuran - CAS 70648-26-9

1,2,3,4,7,8-Hexachlorodibenzofuran - CAS 70648-26-9

MF-0035816-01

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Product Details

  • Bioactivity

    1,2,3,4,7,8-Hexachlorodibenzofuran (1,2,3,4,7,8-HxCDF) enhances the expression of CYP1A1, CYP1B1, and aryl hydrocarbon receptor repressor (AhRR) genes in human peripheral blood lymphocytes (PBL) . It can activate ethoxyresorufin-O-deethylase (EROD), with a BMR20TCDD within the range of 0.115-0.143 nM, corresponding to 20% of the maximum response induced by TCDD.

  • Target

    Cytochromes P450, Aryl Hydrocarbon Receptor

  • Related Pathways

    Metabolism, Immunology/Inflammation

  • CAS Number

    70613

  • Molecular Formula

    C12H2Cl6O

  • Molecular Weight

    374.86

  • SMILES

    ClC1=CC=2OC3=C(Cl)C(Cl)=C(Cl)C(Cl)=C3C2C=C1Cl

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound