1,2-Dilinoleoyl-sn-glycero-3-phospho-L-serine sodium - CAS 321883-39-0

1,2-Dilinoleoyl-sn-glycero-3-phospho-L-serine sodium is a lipid compound utilized in the formulation of liposomes. Liposomes, composed of concentric phospholipid bilayer vesicles, serve as integral components in drug delivery systems aimed at oncology and anti-infection treatments. They efficiently encapsulate hydrophilic (highly polar) solutes within their aqueous interior, while lipophilic solutes are integrated into and become part of the lipid bilayer. This compound is particularly effective in delivering antisense oligonucleotides, addressing challenges such as poor cellular uptake and rapid degradation in the body.

Liposome

Metabolism

321844

C42H73NNaO10P

805.99

[O-]C([C@@H](N)COP(OC[C@@H](COC(CCCCCCC/C=C\C/C=C\CCCCC)=O)OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)(O)=O)=O.[Na+]

-20°C

Ice Packs

Inhibitors & Agonists