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1- (4-Chloro-3- (trifluoromethyl) phenyl) -3- (4- (4-cyanophenoxy) phenyl) urea - CAS 1313019-65-6

1- (4-Chloro-3- (trifluoromethyl) phenyl) -3- (4- (4-cyanophenoxy) phenyl) urea - CAS 1313019-65-6

MF-0053332-01

$36.16 USD
$36.16 USD
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Product Details

  • Bioactivity

    Compound SC-1 is a a derivative of the multiple tyrosine kinase inhibitor sorafenib. Compound SC-1 potently inhibits the phosphorylation of STAT3 by blocking STAT3 phosphorylation and activation, and induces apoptosis in hepatocellular carcinoma cell lines[1].

  • Target

    STAT, Apoptosis

  • Related Pathways

    Apoptosis, Stem Cells, JAK/STAT signaling

  • CAS Number

    1312948

  • Purity

    0.9941

  • Molecular Formula

    C21H13ClF3N3O2

  • Molecular Weight

    431.8

  • SMILES

    FC(F)(F)C1=CC(NC(=O)NC2=CC=C(OC3=CC=C(C=C3)C#N)C=C2)=CC=C1Cl

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound