1,4-D-Gulonolactone - CAS 6322-07-2

1,4-D-Gulonolactone (D-Gulonic acid γ-lactone) (also known as reduced ascorbic acid, RAA) is the substrate of the enzyme L-gulono-1,4-lactone oxidoreductase (EC 1.1.3.8), which catalyzes the last step of the biosynthesis of L-ascorbic acid (vitamin C) in plants and animals. The enzyme L-Gulono-1,4-lactone oxidase is missing in scurvy-prone, vitamin C-deficient animals, such as humans. 1,4-D-Gulonolactone is present in human blood and has been used as one of the markers to compare changes in exercise-induced oxidative stress.

Endogenous Metabolite

Metabolism

6322-07-2

0.9974

C6H10O6

178.14

OC[C@@H](O)[C@@H]1OC(=O)[C@H](O)[C@@H]1O

-20°C

Ice Packs

Natural Product