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1,5-Isoquinolinediol - CAS 5154-02-9
1,5-Isoquinolinediol - CAS 5154-02-9
SKU:MF-0013776-01
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$31.68 USD
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Product Details
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Bioactivity
1, 5-Isoquinolinediol is an inhibitor of poly (ADP-ribose) synthetase (PARP1; IC50: 0.39 μM) . The poly (ADP-ribose) polymerases (PARPs) form a family of enzymes with roles in DNA repair and apoptosis. 1, 5-Isoquinolinediol has been used to study the role of PARP1 in both DNA repair and oxidant stress-induced cell death. This compound can be used with cells in culture and in animals.
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Target
PARP
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Related Pathways
DNA Damage/DNA Repair, Chromatin/Epigenetic
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CAS Number
5154-02-9
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Purity
0.9943
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Molecular Formula
C9H7NO2
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Molecular Weight
161.16
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SMILES
Oc1cccc2c(O)nccc12
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound