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Molfinity

1,5-Isoquinolinediol - CAS 5154-02-9

1,5-Isoquinolinediol - CAS 5154-02-9

SKU:MF-0013776-01

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  • Bioactivity

    1, 5-Isoquinolinediol is an inhibitor of poly (ADP-ribose) synthetase (PARP1; IC50: 0.39 μM) . The poly (ADP-ribose) polymerases (PARPs) form a family of enzymes with roles in DNA repair and apoptosis. 1, 5-Isoquinolinediol has been used to study the role of PARP1 in both DNA repair and oxidant stress-induced cell death. This compound can be used with cells in culture and in animals.

  • Target

    PARP

  • Related Pathways

    DNA Damage/DNA Repair, Chromatin/Epigenetic

  • CAS Number

    5154-02-9

  • Purity

    0.9943

  • Molecular Formula

    C9H7NO2

  • Molecular Weight

    161.16

  • SMILES

    Oc1cccc2c(O)nccc12

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound