1,7-Diphenyl-4-hepten-3-one - CAS 79559-59-4

1,7-Diphenyl-4-hepten-3-one is a compound isolated from Alpinia officinarum, which activates the Nrf2 pathway to suppress pyroptosis. It alleviates cognitive impairment and pathological damage in APP/PS1 mice and prevents oxidative stress damage while reducing levels of pyroptosis-related proteins. 1,7-Diphenyl-4-hepten-3-one enhances Aβ-induced proliferation in HT22 cells and can be used in Alzheimer’s disease research.

Pyroptosis, Nrf2

Immunology/Inflammation, Apoptosis

79496

C19H20O

264.36

O=C(C=CCCC=1C=CC=CC1)CCC=2C=CC=CC2

-20°C

Ice Packs

Natural Product