1-Decarboxy-3-oxo-ceanothic acid - CAS 214150-74-0

1-Decarboxy-3-oxo-ceanothic acid exhibits in vitro cytotoxic activity in a human ovarian adenocarcinoma cell line, mediated at least in part by induction of apoptosis. It is cytotoxic against OVCAR-3 and HeLa cancer cell lines with IC50 values of 2.8 and 6.6 microg/mL, respectively, and has an IC50 of 11.3 microg/mL against normal cell line FS-5.

DNA/RNA Synthesis, Apoptosis

Apoptosis, Cell Cycle/Checkpoint, DNA Damage/DNA Repair

214150-74-0

C29H44O3

440.668

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-20°C

Ice Packs

Natural Product