1-Dehydro-[10]-gingerdione - CAS 136826-50-1

1-Dehydro-[10]-gingerdione inhibits IKKβ activity by targeting its activation loop, thereby preventing IKKβ-mediated phosphorylation of IκBα in macrophages stimulated by agonists. Furthermore, this compound suppresses LPS-induced NF-κB transcriptional activity, highlighting its potential in research related to NF-κB-associated inflammation and autoimmune disorders [1].

NF-κB, IκB/IKK, Others

NF-κB, Others

136775

C21H30O4

346.46

C(=CC(CC(CCCCCCCCC)=O)=O)C1=CC(OC)=C(O)C=C1

-20°C

Ice Packs

Natural Product