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1-Deoxysphingosine (m18:1 (14Z) ) - CAS 2190487-94-4
1-Deoxysphingosine (m18:1 (14Z) ) - CAS 2190487-94-4
SKU:MF-0053511-01
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Product Details
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Bioactivity
1-Deoxysphingosine (m18:1 (14Z) ) is an unconventional sphingolipid featuring a (14Z) double bond at the n-4 position, synthesized when serine palmitoyltransferase combines palmitoyl-CoA with alanine, not serine, during sphingolipid production. Unlike typical sphingolipids, it lacks the essential C1-hydroxyl group for standard degradation but undergoes metabolism by cytochrome P450 (CYP) subfamilies CYP4A and CYP4F in MEF cells.
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Target
Others
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Related Pathways
Others
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CAS Number
2190487-94-4
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Molecular Formula
C18H37NO
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Molecular Weight
283.5
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SMILES
C(CC[C@H]([C@H](C)N)O)CCCCCCC/C=C\CCC
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound