1-Methyl-2-undecyl-4 (1H) -quinolone - CAS 59443-02-6

1-Methyl-2-undecyl-4 (1H) -quinolone, along with dihydroevocarpine and evodiamine, should serve as chemical markers for the quality control of Evodia rutaecarpa (Juss.) Benth. This compound selectively inhibits type B MAO (MAO-B) activity with an IC (50) value of 15.3 microM using the substrate kynuramine, while not inhibiting type A MAO (MAO-A) activity. It can mitigate high phosphate-induced calcification in human aortic valve interstitial cells (HAVICs) by inhibiting phosphate cotransporter (PiT-1) gene expression and exhibits moderate antiangiogenic activity against human tumor cells.

MAO, Monoamine Oxidase

Metabolism, Neuroscience

59443-02-6

C21H31NO

313.48

CCCCCCCCCCCc1cc(=O)c2ccccc2n1C

-20°C

Ice Packs

Natural Product