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1-Naphthohydroxamic acid - CAS 6953-61-3

1-Naphthohydroxamic acid - CAS 6953-61-3

MF-0018880-01

$31.68 USD
$31.68 USD
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Product Details

  • Bioactivity

    1-Naphthohydroxamic acid (Compound 2) is a potent and selective HDAC8 inhibitor with an IC50 of 14 μM, demonstrating greater selectivity for HDAC8 than class I HDAC1 and class II HDAC6 (IC50 >100 μM) . It does not increase global histone H4 acetylation or reduce total intracellular HDAC activity but can induce tubulin acetylation[1][2].

  • Target

    HDAC

  • Related Pathways

    DNA Damage/DNA Repair, Chromatin/Epigenetic

  • CAS Number

    6889

  • Purity

    >99.99%

  • Molecular Formula

    C11H9NO2

  • Molecular Weight

    187.19

  • SMILES

    ONC(=O)c1cccc2ccccc12

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound