1-Phenylbiguanide HCl - CAS 55-57-2

Compound PDK0269, as 5-HT3 receptor agonists (3–100 μM, pEC50 5.05±0.06), acutely increased XII (hypoglossal) burst frequency and regularity, and decreased bursts/episode . Phenylbiguanide produced a dose-related (10-500 microM) increase in the release of dopamine (280-2000%) . When nomifensine (5 microM) was included in the Ringer solution, the effect of Compound PDK0269 on the release of dopamine was ameliorated or inhibited.

Others, 5-HT Receptor

Neuroscience, Others, GPCR/G Protein

-4

0.9931

C8H12ClN5

213.67

Cl.NC(N)=NC(=N)NC1=CC=CC=C1

-20°C

Ice Packs

Fragment Compound