1-Stearoyl-2-15 (S) -HpETE-sn-glycero-3-PE - CAS 154436-49-4

1-Stearoyl-2-15 (S) -HpETE-sn-glycero-3-PE is a phospholipid with stearic acid at the sn-1 position and 15 (S) -HpETE at the sn-2 position, produced by oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PE by 15-lipoxygenase (15-LO) . At concentrations of 0.6 and 0.9 μM, it increases ferroptotic cell death in wild-type and Acsl4 knockout Pfa1 mouse embryonic fibroblasts (MEFs) treated with the GPX4 inhibitor RSL3.

Ferroptosis, Others

Others, Apoptosis

154383

C43H78NO10P

800.068

CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(O)(=O)OCCN)OC(=O)CCC\C=C/C\C=C/C\C=C/C=C/[C@H](CCCCC)OO

-20°C

Ice Packs

Small Compound