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1-Stearoyl-2-Docosahexaenoyl-sn-glycero-3-PE - CAS 96998-01-5
1-Stearoyl-2-Docosahexaenoyl-sn-glycero-3-PE - CAS 96998-01-5
SKU:MF-0053785-01
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Product Details
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Bioactivity
1-Stearoyl-2-docosahexaenoyl-sn-glycero-3-phosphoethanolamine (18:0-22:6 PE) is a lipid compound utilized in the preparation of liposomes. Liposomes, forming the central component of concentric phospholipid bilayer vesicles, are pivotal in constructing drug delivery systems for anti-cancer and anti-infection applications. They effectively encapsulate hydrophilic payloads within their aqueous internal spaces, while lipophilic compounds are integrated into and become part of the lipid bilayer. This compound is particularly effective for delivering antisense oligonucleotides, addressing challenges such as inefficient cellular uptake and rapid loss in the body.
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Target
Liposome
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Related Pathways
Metabolism
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CAS Number
96998-01-5
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Molecular Formula
C45H78NO8P
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Molecular Weight
792.08
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SMILES
[C@@H](OC(CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CC)=O)(COC(CCCCCCCCCCCCCCCCC)=O)COP(OCCN)(=O)O
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Inhibitors & Agonists