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(±) -10-Hydroxycamptothecin - CAS 64439-81-2

(±) -10-Hydroxycamptothecin - CAS 64439-81-2

SKU:MF-0032793-01

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  • Bioactivity

    (±) -10-Hydroxycamptothecin (Hydroxy Camptothecine) is an alkaloid isolated from the stem wood of the Chinese tree, Camptotheca acuminata. This compound selectively inhibits the nuclear enzyme DNA topoisomerase, type I. Several semisynthetic analogs of camptothecin have demonstrated antitumor activity.

  • Target

    Topoisomerase

  • Related Pathways

    DNA Damage/DNA Repair

  • CAS Number

    64356

  • Purity

    0.9958

  • Molecular Formula

    C20H16N2O5

  • Molecular Weight

    364.35

  • SMILES

    CCC1(O)C(=O)OCc2c1cc1-c3nc4ccc(O)cc4cc3Cn1c2=O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Natural Product