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11β-HSD1-IN-6 - CAS 1303515-33-4
11β-HSD1-IN-6 - CAS 1303515-33-4
SKU:MF-0054059-01
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$1,927.85 USD
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Product Details
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Bioactivity
11β-HSD1-IN-6 is a potent inhibitor of 11β hydroxysteroid dehydrogenase enzymes (11β-HSDs), which catalyze the conversion of active glucocorticoids, corticosterone or cortisol, to their inactive forms, 11-dehydrocorticosterone (11-DHC) and cortisone. The compound specifically targets and inhibits 11β-HSD-1, modulating the interconversion of these glucocorticoids. [1]
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Target
Others, Dehydrogenase
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Related Pathways
Others, Metabolism
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CAS Number
1303478
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Molecular Formula
C21H19ClN4O
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Molecular Weight
378.86
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SMILES
Cl.[H][C@]12Cc3ccc(cc3[C@@]1([H])CCCN2C(=O)c1ccc2nc[nH]c2c1)C#N
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound