11-keto Fluprostenol - CAS 62145-07-7

11-Keto Fluprostenol, a potent analog of prostaglandin F2α (PGF2α), primarily interacts with the FP receptor. It is a structurally modified derivative of prostaglandin D2 (PGD2) designed to enhance its potency and extend its half-life. The compound is produced by oxidizing fluprostenol at the C-11 position, which results in 11-keto fluprostenol. This modification allows 11-keto Fluprostenol to exhibit moderate affinity for the CRTH2/DP2 receptor, though it shows negligible activity at the DP1 receptor, distinguishing its action from that of PGD2.

Others, Prostaglandin Receptor

Immunology/Inflammation, GPCR/G Protein, Others

22004224

C23H27F3O6

456.458

O[C@@H](COc1cccc(c1)C(F)(F)F)\C=C\[C@@H]1[C@@H](C\C=C/CCCC(O)=O)[C@@H](O)CC1=O

-20°C

Ice Packs

Small Compound