11α-O-Benzoyl-12β-O-acetyltenacigenin B - CAS 154022-52-3

11α-O-Benzoyl-12β-O-acetyltenacigenin B, a derivative of Tenacigenin B from Marsdenia tenacissima, functions as an inhibitor of P-glycoprotein (Pgp) . This compound has demonstrated its ability to counteract multidrug resistance (MDR) associated with the overexpression of P-glycoprotein (Pgp) in HepG2/Dox cells. It shows promise for applications in cancer research.

P-gp

Membrane transporter/Ion channel, Neuroscience

154022-52-3

C30H38O7

510.62

C[C@@]12[C@@]3([C@@]4(O3)[C@]([C@H](OC(=O)C5=CC=CC=C5)[C@H]1OC(C)=O)([C@]6(C)[C@@](CC4)(C[C@@H](O)CC6)[H])[H])CC[C@H]2C(C)=O

-20°C

Ice Packs

Natural Product