11alpha-Hydroxyprogesterone - CAS 80-75-1

11alpha-Hydroxyprogesterone, an inactive analogue of 11beta-Hydroxyprogesterone, serves as an experimental control. Meanwhile, 11beta-Hydroxyprogesterone functions as a potent inhibitor of 11β-Hydroxysteroid dehydrogenase and activates the human mineralocorticoid receptor in COS-7 cells, with an effective dose (ED) 50 of 10 nM.

Others, Dehydrogenase

Metabolism, Others

80-75-1

C21H30O3

330.468

[H][C@@]12CC[C@H](C(C)=O)[C@@]1(C)C[C@@H](O)[C@@]1([H])[C@@]2([H])CCC2=CC(=O)CC[C@]12C

-20°C

Ice Packs

Small Compound