12,14-Dichlorodehydroabietic acid - CAS 65281-77-8

12,14-Dichlorodehydroabietic acid, a chlorinated resin acid, exhibits potent calcium-activated potassium (BK) channel opening activity, effectively inhibits GABA-dependent chloride influx in the mammalian brain as a non-competitive antagonist of GABA A receptors, induces elevation in cytosolic free calcium levels, and promotes neurotransmitter release.

Others, GABA Receptor, Potassium Channel

Others, Neuroscience, Membrane transporter/Ion channel

65196

C20H26Cl2O2

369.33

[H][C@@]12CCc3c(Cl)c(C(C)C)c(Cl)cc3[C@@]1(C)CCC[C@@]2(C)C(O)=O

-20°C

Ice Packs

Small Compound