[12]-Dehydrogingerdione - CAS 99742-05-9

[12]-Dehydrogingerdione is a natural product found in ginger that has anti-neuroinflammatory activity, possibly by inhibiting the Akt/IKK/IκB/NF-κB pathway and promoting the Nrf-2/HO-1 pathway to prevent neuroinflammation. 12-Dehydrogingerdione can inhibit the production of NO, IL-6, and PGE2 in LPS-stimulated Raw 264.7 cells.

Others, Interleukin, NO Synthase

Immunology/Inflammation, Others

99742-05-9

C23H34O4

374.51

C(=C/C(=CC(CCCCCCCCCCC)=O)O)\C1=CC(OC)=C(O)C=C1

-20°C

Ice Packs

Natural Product