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Molfinity

12-Hydroxynevirapine - CAS 133627-24-4

12-Hydroxynevirapine - CAS 133627-24-4

MF-0054102-01

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Product Details

  • Bioactivity

    12-Hydroxynevirapine (12-hydroxy-NVP; 12-OH-NVP), a significant oxidative metabolite of Nevirapine—an antiviral drug for HIV-1 infections known for potential idiosyncratic hepatotoxicity and skin rashes—undergoes bioactivation through sulphotransferases (SULTs) in the liver and skin to form the reactive species 12-Sulphoxy-nevirapine [1] [2].

  • Target

    Others, Drug Metabolite

  • Related Pathways

    Others, Metabolism

  • CAS Number

    133599

  • Molecular Formula

    C15H14N4O2

  • Molecular Weight

    282.3

  • SMILES

    OCc1ccnc2N(C3CC3)c3ncccc3C(=O)Nc12

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound