12 (S) -HETE - CAS 54397-83-0

12 (S) -HETE, a 12-lipoxygenase metabolite of arachidonic acid, is mitogenic for cancer cell proliferation and enhances angiotensin II-induced contraction of BLT2 (type 2 receptor in arteries of leukotriene B4 mice) and TP (thromboxane receptor) -mediated mechanisms. 12 (S) -HETE promotes superoxide and isothromboxane-like metabolites in arterial endothelial cells. production.

DNA/RNA Synthesis, p38 MAPK, ERK

DNA Damage/DNA Repair, MAPK, Cell Cycle/Checkpoint

54314

C20H32O3

320.47

C(\[C@H](C/C=C\CCCCC)O)=C/C=C\C/C=C\CCCC(O)=O

-20°C

Ice Packs

Small Compound