15-Deoxy-Δ12,14-Prostaglandin J2-2-glyceryl ester - CAS 1947405-90-4

15-Deoxy-Δ12,14-Prostaglandin J2-2-glyceryl ester is a derivative of 15-Deoxy-Δ-12,14-prostaglandin J2. The 15-Deoxy-Δ-12,14-prostaglandin J2 (15d-PGJ2) is a cyclopentenone prostaglandin and a metabolite of PGD2. This compound acts as a selective PPARγ (with an EC50 of 2 μM) and covalent PPARδ agonist. Additionally, 15-Deoxy-Δ-12,14-prostaglandin J2 effectively promotes the differentiation of C3H10T1/2 fibroblasts into adipocytes, with an EC50 of 7 μM.

Others, PPAR, Endogenous Metabolite

Others, Metabolism, DNA Damage/DNA Repair

1947311

C23H34O5

390.51

C(\C=C\CCCCC)=C/1\[C@@H](C/C=C\CCCC(OC(CO)CO)=O)C=CC1=O

-20°C

Ice Packs

Small Compound