(±) 17-HETE - CAS 128914-47-6

Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. (±) 17-HETE is the racemic version of a cytochrome P450 (CYP450) metabolite of arachidonic acid that has stereospecific effects on sodium transport in the kidney. At a concentration of 2 μM the (S) -enantiomer of 17-HETE inhibits proximal tubule ATPase activity by as much as 70%, whereas the (R) -isomer is inactive.

Others, ATPase, Cytochromes P450

Metabolism, Membrane transporter/Ion channel, Others

128861

C20H32O3

320.473

CCCC(O)C\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O

-20°C

Ice Packs

Small Compound