17-oxo-7 (Z),10 (Z),13 (Z),15 (E),19 (Z) -Docosapentaenoic Acid - CAS 1233715-33-7

Docosapentaenoic acid (DPA) is a ω-3 fatty acid found in fish oils. 17-oxo-7 (Z),10 (Z),13 (Z),15 (E),19 (Z) -docosapentaenoic acid is a metabolite of lipoxygenase-mediated oxidation of DPA that is produced endogenously by aspirin-enhanced COX-2 activity. It has been shown to activate Nrf2-dependent antioxidant gene expression, to act as a PPARγ agonist (EC50 = ~200 nM), and to inhibit pro-inflammatory cytokine and nitric oxide production at biological concentration ranges (5-25 μM) .

Others, PPAR, NF-κB

Metabolism, NF-κB, Others, DNA Damage/DNA Repair

1233715-33-7

C22H32O3

344.495

CC\C=C/CC(=O)\C=C\C=C/C\C=C/C\C=C/CCCCCC(O)=O

-20°C

Ice Packs

Small Compound