2',3'-cGAMP sodium - CAS 2734858-36-5

2',3'-cGAMP sodium (2'-3'-cyclic GMP-AMP sodium) is a second messenger in cellular innate immunity, catalyzed by cGAMP synthase (cGAS) under DNA binding conditions. It binds to STING to form a dimer, inducing the production and expression of interferon-β and other cytokines.

IFNAR, cGAS, STING, Endogenous Metabolite

Immunology/Inflammation, Metabolism

2734817

0.9984

C20H22N10Na2O13P2

718.37

OC1([H])[C@](OP(OC[C@](O[C@@H](N2C3=NC=NC(N)=C3N=C2)[C@@H]4O)([H])[C@@]4([H])O5)(O[Na])=O)([H])[C@H](N6C(NC(N)=NC7=O)=C7N=C6)O[C@]1([H])COP5(O[Na])=O

-20°C

Ice Packs

Natural Product