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2,3-Dehydro-3,4-dihydro ivermectin - CAS 1135339-49-9

2,3-Dehydro-3,4-dihydro ivermectin - CAS 1135339-49-9

SKU:MF-0036001-01

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  • Bioactivity

    2,3-Dehydro-3,4-dihydro ivermectin, an ivermectin analog and anthelmintic, demonstrates efficacy against L. amazonensis promastigotes and amastigotes, with IC50 values of 13.8 μM and 3.6 μM, respectively, while maintaining a low cytotoxicity profile in macrophages (IC50 = 65.5 μM) .

  • Target

    Parasite, Others

  • Related Pathways

    Others, Microbiology/Virology

  • CAS Number

    1135339-49-9

  • Molecular Formula

    C48H74O14

  • Molecular Weight

    875.106

  • SMILES

    CC[C@H](C)[C@H]1O[C@]2(CC[C@@H]1C)C[C@@H]1C[C@@H](C\C=C(C)\[C@@H](O[C@H]3C[C@H](OC)[C@@H](O[C@H]4C[C@H](OC)[C@H](O)[C@H](C)O4)[C@H](C)O3)[C@@H](C)\C=C\C=C3/CO[C@@H]4[C@H](O)C(C)C=C(C(=O)O1)[C@]34O)O2

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound