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2,3-Dehydro-3,4-dihydro ivermectin - CAS 1135339-49-9
2,3-Dehydro-3,4-dihydro ivermectin - CAS 1135339-49-9
SKU:MF-0036001-01
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Product Details
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Bioactivity
2,3-Dehydro-3,4-dihydro ivermectin, an ivermectin analog and anthelmintic, demonstrates efficacy against L. amazonensis promastigotes and amastigotes, with IC50 values of 13.8 μM and 3.6 μM, respectively, while maintaining a low cytotoxicity profile in macrophages (IC50 = 65.5 μM) .
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Target
Parasite, Others
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Related Pathways
Others, Microbiology/Virology
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CAS Number
1135339-49-9
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Molecular Formula
C48H74O14
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Molecular Weight
875.106
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SMILES
CC[C@H](C)[C@H]1O[C@]2(CC[C@@H]1C)C[C@@H]1C[C@@H](C\C=C(C)\[C@@H](O[C@H]3C[C@H](OC)[C@@H](O[C@H]4C[C@H](OC)[C@H](O)[C@H](C)O4)[C@H](C)O3)[C@@H](C)\C=C\C=C3/CO[C@@H]4[C@H](O)C(C)C=C(C(=O)O1)[C@]34O)O2
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound