2,3-dinor Prostaglandin E1 - CAS 7046-40-4

Prostaglandin E1 (PGE1), though not predominantly found in nature, plays a significant role in clinical treatments, addressing conditions such as peripheral occlusive vascular disease, erectile dysfunction, and neonatal cardiology issues. The metabolism of PGE1 primarily begins with the oxidation at C-15, producing 13,14-dihydro-15-keto PGE1 as its major metabolite. Alternatively, inhibiting this pathway or overwhelming it with too much PGE1 could potentially enhance the production of 2,3-dinor metabolites, like 2,3-dinor PGE1, though their biological activities remain unreported. Cayman Chemical stands out as a prominent provider of prostaglandins and their metabolites, uniquely manufacturing 2,3-dinor PGE1.

Endogenous Metabolite, Others, Prostaglandin Receptor

Metabolism, Others, Immunology/Inflammation, GPCR/G Protein

7046-40-4

C18H30O5

326.4

C(CCCC(O)=O)[C@@H]1[C@@H](/C=C/[C@H](CCCCC)O)[C@H](O)CC1=O

-20°C

Ice Packs

Small Compound