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2,3-Diphospho-D-glyceric acid pentasodium salt - CAS 102783-53-9
2,3-Diphospho-D-glyceric acid pentasodium salt - CAS 102783-53-9
SKU:MF-0055184-01
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Product Details
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Bioactivity
2,3-Diphospho-D-glyceric acid pentasodium salt is a highly anionic polyphosphorus compound located within the concave center of red blood cells, where it decreases oxygen affinity by binding to hemoglobin. This endogenous compound selectively inhibits vascular calcification (VC) and effectively postpones the formation of crystalline calpain particles (CPP) . Additionally, it inhibits calcification in the mouse vascular smooth muscle cell line (MOVAS) without eliciting cytotoxic effects [1].
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Target
Others, Endogenous Metabolite
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Related Pathways
Others, Metabolism
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CAS Number
102783-53-9
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Molecular Formula
C3H3Na5O10P2
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Molecular Weight
375.95
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SMILES
O=P([O-])([O-])OC[C@H](C([O-])=O)OP([O-])([O-])=O.[Na+].[Na+].[Na+].[Na+].[Na+]
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound