2',6'-Dihydroxy 4'-methoxydihydrochalcone - CAS 35241-55-5

2',6'-Dihydroxy 4'-methoxydihydrochalcone is an orally active dihydrochalcone with antiplasmodial and anti-inflammatory activity, reducing IL-1β, TNF, and nitrite production in vitro while modulating macrophage inflammatory protein secretion and preventing L-selectin cleavage in neutrophils. Toxicological evaluation showed no significant acute toxicity, reinforcing its applicability for inflammation-related pharmacology and infectious disease studies.

IL Receptor, TNF

Apoptosis, Immunology/Inflammation

35181

C16H16O4

272.3

O=C(C=1C(O)=CC(OC)=CC1O)CCC=2C=CC=CC2

-20°C

Ice Packs

Natural Product