2'-Deoxyguanosine monohydrate - CAS 312693-72-4

2'-Deoxyguanosine monohydrate (Guanine-2'-deoxyriboside) is a nucleoside consisting of the base guanine and the sugar deoxyribose. It is like guanosine, but with one oxygen atom removed. It is a nucleoside component of DNA. 2'-Deoxyguanosine monohydrate can be converted to 8-hydroxy-deoxyguanosine (8-OHdG) due to hydroxyl radical attack at the C8 of guanine. 8-OHdG is a sensitive marker of the DNA damage This damage, if left unrepaired, has been proposed to contribute to mutagenicity and cancer promotion.

Endogenous Metabolite

Metabolism

312617

0.9973

C10H15N5O5

285.26

O.Nc1nc2n(cnc2c(=O)[nH]1)[C@H]1C[C@H](O)[C@@H](CO)O1

-20°C

Ice Packs

Natural Product