Molfinity
2'-Hydroxychalcone - CAS 1214-47-7
2'-Hydroxychalcone - CAS 1214-47-7
SKU:MF-0011979-01
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Product Details
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Bioactivity
2'-Hydroxychalcone is a drug synthesis intermediate for the synthesis of flavonoids. 2'-Hydroxychalcone loaded in nanoemulsion showed fungicidal activity against Coccidioides parapsilosis in Danio rerio model.2'-Hydroxychalcone induced cytotoxicity through oxidative stress in lipid-loaded Hepg2 cells.2'-Hydroxychalcone inhibited the induction of ICAM-1, VCAM-α, tumor necrosis factor-α, and tumor necrosis factor-alpha as determined by reverse transcription-polymerase chain reaction determined by tumor necrosis factor-alpha induces steady-state transcript levels of ICAM-1, VCAM-1, and E-selectin, and therefore may interfere with the transcription of their genes.
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Target
Others, Autophagy, Antifungal, Apoptosis, NF-κB
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Related Pathways
Apoptosis, Others, NF-κB, Microbiology/Virology, Autophagy
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CAS Number
1214-47-7
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Purity
0.9854
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Molecular Formula
C15H12O2
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Molecular Weight
224.25
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SMILES
Oc1ccccc1C(=O)\C=C\c1ccccc1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Natural Product