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Molfinity

2'-Hydroxychalcone - CAS 1214-47-7

2'-Hydroxychalcone - CAS 1214-47-7

SKU:MF-0011979-01

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  • Bioactivity

    2'-Hydroxychalcone is a drug synthesis intermediate for the synthesis of flavonoids. 2'-Hydroxychalcone loaded in nanoemulsion showed fungicidal activity against Coccidioides parapsilosis in Danio rerio model.2'-Hydroxychalcone induced cytotoxicity through oxidative stress in lipid-loaded Hepg2 cells.2'-Hydroxychalcone inhibited the induction of ICAM-1, VCAM-α, tumor necrosis factor-α, and tumor necrosis factor-alpha as determined by reverse transcription-polymerase chain reaction determined by tumor necrosis factor-alpha induces steady-state transcript levels of ICAM-1, VCAM-1, and E-selectin, and therefore may interfere with the transcription of their genes.

  • Target

    Others, Autophagy, Antifungal, Apoptosis, NF-κB

  • Related Pathways

    Apoptosis, Others, NF-κB, Microbiology/Virology, Autophagy

  • CAS Number

    1214-47-7

  • Purity

    0.9854

  • Molecular Formula

    C15H12O2

  • Molecular Weight

    224.25

  • SMILES

    Oc1ccccc1C(=O)\C=C\c1ccccc1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Natural Product