2-Methyl estradiol - CAS 1818-12-8

2-Methyl estradiol is an endogenous metabolite of estradiol that inhibits cell proliferation and angiogenesis. The IC50 values for its effects on the proliferation of HUVEC (human umbilical vein endothelial cells) and MCF-7 (human breast cancer cells) are 3 μM and 2.39 μM, respectively.

Endogenous Metabolite

Metabolism

1818-12-8

C19H26O2

286.409

C[C@@]12[C@]([C@]3([C@@](C=4C(CC3)=CC(O)=C(C)C4)(CC1)[H])[H])(CC[C@@H]2O)[H]

-20°C

Ice Packs

Natural Product