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2-O-methyl PAF C-16 - CAS 78858-44-3

2-O-methyl PAF C-16 - CAS 78858-44-3

SKU:MF-0056220-01

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  • Bioactivity

    2-O-methyl PAF C-16 is a synthetic analog of platelet-activating factor (PAF) featuring a methyl group attached via an ether linkage at the sn-2 position. While the specific biological activities of 2-O-methyl PAF C-16 remain undercharacterized, studies with its C-18 counterpart have demonstrated its ability to modulate various biological processes. These processes include reducing plasma membrane fluidity and hindering the invasiveness of tumor cells in embryonic chick hearts. Furthermore, in rat astrocytes, the C-18 analog prompts the release of significant amounts of nitric oxide (NO) through a mechanism that involves the activation of nitric oxide synthase (NOS) .

  • Target

    Others, TNF

  • Related Pathways

    Apoptosis, Others

  • CAS Number

    78858-44-3

  • Molecular Formula

    C25H54NO6P

  • Molecular Weight

    495.7

  • SMILES

    [C@H](COP(OCC[N+](C)(C)C)(=O)[O-])(COCCCCCCCCCCCCCCCC)OC

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound