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2-O-methyl PAF C-16 - CAS 78858-44-3
2-O-methyl PAF C-16 - CAS 78858-44-3
SKU:MF-0056220-01
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Product Details
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Bioactivity
2-O-methyl PAF C-16 is a synthetic analog of platelet-activating factor (PAF) featuring a methyl group attached via an ether linkage at the sn-2 position. While the specific biological activities of 2-O-methyl PAF C-16 remain undercharacterized, studies with its C-18 counterpart have demonstrated its ability to modulate various biological processes. These processes include reducing plasma membrane fluidity and hindering the invasiveness of tumor cells in embryonic chick hearts. Furthermore, in rat astrocytes, the C-18 analog prompts the release of significant amounts of nitric oxide (NO) through a mechanism that involves the activation of nitric oxide synthase (NOS) .
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Target
Others, TNF
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Related Pathways
Apoptosis, Others
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CAS Number
78858-44-3
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Molecular Formula
C25H54NO6P
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Molecular Weight
495.7
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SMILES
[C@H](COP(OCC[N+](C)(C)C)(=O)[O-])(COCCCCCCCCCCCCCCCC)OC
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound