2-PPA - CAS 21203-86-1

2-PPA serves as a selective TMEM175 inhibitor (IC 50 =32 μM), primarily influencing lysosomal activity. Through acute inhibition of TMEM175, 2-PPA enhances lysosomal macromolecular catabolism, which in turn boosts macrophage activity and other digestive processes. This compound holds significance in Parkinson's disease research.

Potassium Channel, Others

Membrane transporter/Ion channel, Others

21203-86-1

C11H10N2

170.21

N=1C=CC(N)=CC1C=2C=CC=CC2

-20°C

Ice Packs

Small Compound