2-Thio-UTP - CAS 35763-29-2

2-Thio-UTP is a selective P2Y2 receptor (purinergic receptor) agonist (EC50 = 50 nM) capable of inhibiting calcification potential, α-smooth muscle actin expression, and pro-fibrotic gene expression in valvular interstitial cells (VICs) . It may be employed in studies of calcific aortic valve stenosis (CAVS) .

Others, P2Y Receptor

Others, Neuroscience, GPCR/G Protein

35732

C9H15N2O14P3S

500.21

O[C@H]1[C@@H](O[C@H](COP(OP(OP(=O)(O)O)(=O)O)(=O)O)[C@H]1O)N2C(=S)NC(=O)C=C2

-20°C

Ice Packs

Small Compound