2-Thiouridine - CAS 20235-78-3

2-Thiouridine (s2U) is a modified nucleobase found in tRNAs that is known to stabilize U:A pairs and modestly destabilize U:G wobble pairs. Modified nucleobases, including 2-thiouridine, are used to study nucleic acid structure and function as well as to engineer novel RNA-based biomolecules.

Anti-infection, Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis, SARS-CoV, Others

Cell Cycle/Checkpoint, DNA Damage/DNA Repair, Microbiology/Virology, Others

20154

C9H12N2O5S

260.27

OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=S

-20°C

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