244cis - CAS 2956402-64-3

244cis, an ionizable cationic lipid incorporating a piperazine structure, facilitates the creation of lipid nanoparticles (LNPs) . These LNPs, when formulated with 244cis and coated with an mRNA reporter gene, exhibit preferential accumulation in the lungs of mice, in contrast to those formulated with SM-102. Additionally, it leads to a reduction in the levels of serum chemokine (C-C motif) ligand 2 (CCL2) [1].

Liposome, Others

Metabolism, Others

2956402-64-3

C60H111N3O6

970.54

C(CN(CCCCCCCCC(OC/C=C\CCCCCC)=O)CCCCCCCCC(OC/C=C\CCCCCC)=O)N1CCN(CCCCCCCCC(OC/C=C\CCCCCC)=O)CC1

-20°C

Ice Packs

Small Compound