28-Acetylbetulin - CAS 27686-35-7

28-Acetylbetulin is a lupane triterpenoid and derivative of the cholesterol biosynthesis inhibitor betulin that has been found inM. chiapensisand has anti-inflammatory and anticancer activities.1,2It inhibits LPS-induced nitric oxide (NO) and prostaglandin E2production by 55.9 and 69.5%, respectively, in RAW 264.7 cells (IC50s = 4.7 and 1.7 μM, respectively) .128-Acetylbetulin induces cytotoxicity in a variety of cancer cells, including A549, HT-29, and MCF-7 cells (IC50s = 14.37, 10.96, and 11.38 μM, respectively) .2

Others

Others

27644

C32H52O3

484.765

[H][C@]12[C@@H](CC[C@]1(COC(C)=O)CC[C@]1(C)[C@]2([H])CC[C@]2([H])[C@@]3(C)CC[C@H](O)C(C)(C)[C@]3([H])CC[C@@]12C)C(C)=C

-20°C

Ice Packs

Small Compound