(2R,3S) -Emricasan - CAS 409369-54-6

(2R,3S) -Emricasan ((2R,3S) -PF 03491390) is an isomer of Emricasan. This compound acts as an orally effective irreversible pan-caspase inhibitor. (2R,3S) -Emricasan inhibits the increase in caspase-3 activity induced by Zika virus (ZIKV) and protects human cortical neural progenitor cells.

Caspase, Anti-infection

Microbiology/Virology, Proteases/Proteasome, Apoptosis

409369-54-6

C26H27F4N3O7

569.5

N(C(C(N[C@@H](C(N[C@H](C(COC1=C(F)C(F)=CC(F)=C1F)=O)CC(O)=O)=O)C)=O)=O)C2=C(C(C)(C)C)C=CC=C2

-20°C

Ice Packs

Small Compound