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(2S) -2'-Methoxykurarinone - CAS 270249-38-2

(2S) -2'-Methoxykurarinone - CAS 270249-38-2

SKU:MF-0002673-01

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  • Bioactivity

    (2S) -2'-Methoxykurarinone is isolated from the roots of Sophora flavescens. (2S) -2'-Methoxykurarinone has anti-inflammatory, antipyretic, antidiabetic, and antineoplastic effects. (2S) -2'-Methoxykurarinone inhibits osteoclastogenesis and bone resorption through down-regulation of RANKL signaling. (2S) -2'-Methoxykurarinone displays cytotoxic activity against human myeloid leukemia HL-60 cells.

  • Target

    RANKL/RANK, Akt, Antifection

  • Related Pathways

    Cytoskeletal Signaling, Microbiology/Virology, NF-κB, PI3K/Akt/mTOR signaling

  • CAS Number

    270209

  • Purity

    0.9944

  • Molecular Formula

    C27H32O6

  • Molecular Weight

    452.54

  • SMILES

    COc1cc(O)ccc1[C@@H]1CC(=O)c2c(OC)cc(O)c(C[C@@H](CC=C(C)C)C(C)=C)c2O1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Natural Product