3,4-Dibromo-Mal-PEG4-Acid - CAS 2434639-17-3

3,4-Dibromo-Mal-PEG4-Acid is a site-specific ADC linker featuring a dibromomaleimide group and an acid group. The presence of two bromine atoms in the dibromomaleimide group allows for two substitution points. In the presence of EDC and HATU, the carboxylic acid can react with primary amines to form stable amide bonds. The hydrophilic PEG linker enhances the compound's solubility in aqueous media.

ADC Linker

Antibody-drug Conjugate/ADC Related

2434639-17-3

C15H21Br2NO8

503.137

O=C(O)CCOCCOCCOCCOCCN1C(=O)C(Br)=C(Br)C1=O

-20°C

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