3β,7β-Dihydroxy-5-cholestenoic acid - CAS 1246298-66-7

3β,7β-Dihydroxy-5-cholestenoic acid is a C27 acid whose levels are elevated in Niemann-Pick Type C and B diseases, leading to toxicity in ocular motor neurons. It is synthesized by the enzymatic action of hydroxysteroid 11-β dehydrogenase 1 from 3β-hydroxy-7-oxocholest-5-en- (25R) 26-enoic acid (3βH,7O-CA) .

Endogenous Metabolite, Others

Metabolism, Others

1246225

C27H44O4

432.64

C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C(=C[C@@H]3O)C[C@@H](O)CC4)(CC1)[H])[H])(CC[C@@]2([C@@H](CCC[C@H](C(O)=O)C)C)[H])[H]

-20°C

Ice Packs

Small Compound