3-Bromotyrosine TFA - CAS 2320428-62-2

3-Bromotyrosine, a product of protein oxidation, is generated after eosinophil activation during allergic responses. It serves as a biomarker for eosinophil peroxidase-induced protein oxidation both in vitro and in vivo. Beyond its association with eosinophils, 3-bromotyrosine levels are significantly elevated in peritoneal exudate from K. pneumoniae-infected mice, indicating a fivefold increase compared to uninfected controls, which implies that neutrophils may release increased levels of oxidized products during inflammation. Furthermore, in humans, allergen-challenged lung samples from patients with allergen-induced asthma show a tenfold increase in 3-bromotyrosine, highlighting its potential as a marker for oxidative stress in allergic conditions.

Others, Amino Acids and Derivatives

Others, Metabolism

2320428-62-2

C11H11BrF3NO5

374.11

OC(=O)C(F)(F)F.N[C@@H](Cc1ccc(O)c(Br)c1)C(O)=O

-20°C

Ice Packs

Small Compound