3-Demethylthiocolchicine - CAS 87424-25-7

3-Demethylthiocolchicine, a colchicine analog, exhibits broad-spectrum antitumor activity and shares similar properties and activities with colchicine in inhibiting casein-induced amyloidosis, microtubule binding, and anti-inflammatory effects. Notably, it has significantly lower toxicity compared to colchicine.

Microtubule Associated

Cytoskeletal Signaling

87392

C21H23NO5S

401.48

O(C)C1=C2C=3C([C@@H](NC(C)=O)CCC2=CC(O)=C1OC)=CC(=O)C(SC)=CC3

-20°C

Ice Packs

Small Compound