3-Deoxyglucosone - CAS 4084-27-9

3-Deoxyglucosone (3-Deoxy-D-glucosone) is synthesized by the intermediate pathway of the melad and polyol reactions.3-Deoxyglucosone reacts rapidly with protein amino groups to form advanced glycosylated end proteins (AGEs) .3-Deoxyglucosone inactivates glutathione peroxidase and synergizes with low glucose to enhance GLP-1 secretion.3-Deoxyglucosone is used as a biomarker for diabetes mellitus.3-Deoxyglucosone has been shown to be an inhibitor of GLP-1 secretion in the presence of low glucose. 3-Deoxyglucosone inactivates glutathione oxidase, synergizes with low glucose to enhance GLP-1 secretion, and can be used as a biologic marker for diabetes.

GPX, Glucagon Receptor

Oxidation-Reduction, GPCR/G Protein

4048

0.95

C6H10O5

162.14

[C@H](CC(C=O)=O)([C@@H](CO)O)O

-20°C

Ice Packs

Natural Product