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3-Fluoro-desmethyl-cabozantinib-C3-O-C3-PEG-acid - CAS 2230826-10-3
3-Fluoro-desmethyl-cabozantinib-C3-O-C3-PEG-acid - CAS 2230826-10-3
SKU:MF-0057339-01
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Product Details
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Bioactivity
3-Fluoro-desmethyl-cabozantinib-C3-O-C3-PEG-acid is a target protein ligand-linker conjugate combining a c-Met ligand with a PROTAC linker to recruit E3 ligase. It is applicable for synthesizing PROTACs, such as SJF-8240.
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Target
C-Met/HGFR, Target Protein Ligand-Linker Conjugate
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Related Pathways
PROTAC, Tyrosine Kinase/Adaptors
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CAS Number
2230813
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Molecular Formula
C36H37F2N3O9
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Molecular Weight
693.69
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SMILES
O=C(O)CCOCCCOCCCOC1=CC2=NC=CC(OC3=CC=C(C=C3F)NC(=O)C4(C(=O)NC5=CC=C(F)C=C5)CC4)=C2C=C1OC
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
PROTAC