3-Hydroxybakuchiol - CAS 178765-54-3

3-Hydroxybakuchiol exerts cytotoxic and anti-proliferative effects on the TA3/Ha mouse mammary adenocarcinoma cell line and induces a decrease in the mitochondrial transmembrane potential, the activation of caspase-3, the opening of the mitochondrial permeability transport pore (MPTP) and nuclear DNA fragmentation.3-Hydroxybakuchiol has antitumor activity resulting from interactions with the ETC, a system that is already deficient in cancer cells.

Glucosidase, Caspase, Apoptosis, ATPase, glycosidase

Proteases/Proteasome, Membrane transporter/Ion channel, Apoptosis, Metabolism

178765-54-3

C18H24O2

272.38

C\C(C)=C\CC[C@@](C)(C=C)\C=C\c1ccc(O)c(O)c1

-20°C

Ice Packs

Natural Product